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5.2 Oral treatment 5.2.1 Tranexamic acid Oral tranexamic acid has been shown to be effective as an adjuvant therapy for refractory cases of melasma or as a second or third-line of treatment (Kim et al., 2017)

301 , R14791485 (2011)

Peer review Peer review information Nature Communications thanks Karl Hoffmann, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work